ATR7000 Series Process Raman Analysers

DESCRIPTION

The ATR7000 Series brings Raman spectroscopy directly into reaction and manufacturing environments where composition must be followed during the process rather than measured only after manual sampling. The family covers permanent online analysis, laboratory and pilot-scale in-situ reaction monitoring, and portable quantitative Raman. Fibre-optic probes, cooled detectors and chemometric modelling allow spectra to be related to chemical composition or process state after a suitable analytical model has been developed and validated.

Product Family

ATR7020 is documented with 532, 638, 785 and 1064 nm excitation configurations.

What PAT Means

Process Analytical Technology (PAT) uses measurements made during a process to understand and control what is happening rather than depending solely on final laboratory analysis.

Raman is useful in PAT because the probe can potentially measure directly in a reaction stream or vessel and water is often less problematic in Raman than in mid-infrared absorption spectroscopy.

However, Raman spectra do not automatically provide concentration.

Quantitative concentration requires a model linking spectra to reference analytical measurements.

How It Works

A laser is transmitted through fibre to a process Raman probe. The laser illuminates the reaction mixture or process stream.

Raman-scattered light is collected by the probe and returns through the optical fibre to the spectrometer.

The software processes each spectrum and can:

• follow characteristic peak changes
• track material conversion
• observe crystal-form changes
• apply a quantitative chemometric calibration
• provide trends or alarms when configured

ATR7010 Configurations

Current exact-product documentation lists:

• ATR7010-532
• ATR7010-638
• ATR7010-785
• ATR7010-1064

The visible/NIR configurations use cooled area-array detectors, while the 1064 nm pathway uses InGaAs detection.

Process Probe Reference

Current ATR7010 documentation specifies:

More specialised high-temperature and chemically resistant probes are documented elsewhere in the process family.

Key Features

• Real-time Raman process monitoring.
• In-situ fibre-optic probes.
• Cooled detectors.
• 532, 638, 785 and 1064 nm pathways.
• Quantitative chemometric modelling.
• Reaction endpoint monitoring.
• Crystal/polymorph tracking.
• Multi-channel configurations.
• Remote communications.
• Long-distance fibre/probe installations where configured.
• High-temperature probe options.
• Laboratory, pilot and production applications.

Applications

• crystallisation
• polymorph transformation
• chemical synthesis
• hydrogenation
• bioprocess monitoring
• pharmaceutical process development
• reaction kinetics
• continuous manufacturing
• pilot-scale optimisation
• raw-material conversion
• reaction endpoint detection

Compatibility and Selection Guidance

Process Raman must be configured around the process connection, not just the spectrometer.

Before ordering, determine:

• chemical composition
• process temperature
• pressure
• probe insertion geometry
• corrosion resistance
• required fibre length
• hazardous-area requirements
• excitation wavelength
• number of channels
• quantitative calibration strategy

A research ATR7010 installation may be quite different from a permanent ATR7000 process cabinet.

Why Source Through ScienceGears

ScienceGears can work with research and process teams to define probe geometry, wavelength, process conditions, channel count and quantitative-model requirements and coordinate technical discussions before quotation.

Frequently Asked Questions

Can Raman directly display concentration?
Only after an appropriate quantitative model has been built and validated against reference concentration data.

Can the probe remain inside the reactor?
Yes for an appropriately specified in-situ probe, provided temperature, pressure, chemical compatibility and sealing requirements are satisfied.

Can the system monitor crystallisation?
Raman can follow crystal-form changes where different polymorphs have distinguishable Raman spectra.

Can one instrument monitor multiple reactors?
Multi-channel process architectures are documented, but probe and switching configuration must be specified.

Which laser wavelength should be used?
It depends on fluorescence, sample optical properties and probe/detector requirements.

Is this the same as electrochemical Raman?
No. Process Raman monitors a chemical process. Raman spectroelectrochemistry combines Raman with controlled electrochemical potential or current and belongs to a separate ScienceGears product pathway.

Contact ScienceGears

Contact ScienceGears with your reactor/process conditions, target analytes, expected concentrations, required number of channels and probe requirements to discuss an ATR7000 Series configuration.